Alessandro Lambiase Selected Research

Nerve Growth Factor (NGF)

1/2022	Long-term clinical efficacy of topical treatment with recombinant human nerve growth factor in neurotrophic keratopathy: a novel cure for a rare degenerative corneal disease?
1/2020	Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study.
12/2019	Cancer stem cells-driven tumor growth and immune escape: the Janus face of neurotrophins.
10/2019	Neurotrophic factors and nerve growth factor in ocular allergy.
2/2019	Nerve Growth Factor Role on Retinal Ganglion Cell Survival and Axon Regrowth: Effects of Ocular Administration in Experimental Model of Optic Nerve Injury.
1/2018	Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis.
1/2018	Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis.
8/2017	Neurotrophic factors and corneal nerve regeneration.
1/2017	Time-Dependent Nerve Growth Factor Signaling Changes in the Rat Retina During Optic Nerve Crush-Induced Degeneration of Retinal Ganglion Cells.
1/2017	Recombinant Human Nerve Growth Factor Treatment Promotes Photoreceptor Survival in the Retinas of Rats with Retinitis Pigmentosa.

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Alessandro Lambiase Research Topics

Disease

14	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 10/2019 - 03/2003
12	Dry Eye Syndromes (Dry Eye Syndrome) 09/2020 - 02/2005
10	Keratitis 03/2022 - 10/2005
10	Inflammation (Inflammations) 03/2022 - 10/2003
8	Hypersensitivity (Allergy) 10/2019 - 01/2003
8	Glaucoma 01/2019 - 11/2008
7	Hyperemia 07/2022 - 05/2003
6	Infections 10/2021 - 10/2005
6	Pruritus (Itching) 01/2017 - 03/2003
6	Ulcer 07/2010 - 10/2006
5	Neoplasms (Cancer) 01/2022 - 08/2009
5	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2021 - 06/2005
5	Cataract (Cataracts) 01/2020 - 10/2003
5	Photophobia (Light Sensitivity) 01/2017 - 03/2003
3	Corneal Diseases (Corneal Disease) 01/2022 - 07/2012
3	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2022 - 01/2016
3	Asthma (Bronchial Asthma) 01/2022 - 05/2003
3	Macular Degeneration (Age-Related Maculopathy) 01/2022 - 01/2009
3	Fibrosis (Cirrhosis) 10/2021 - 10/2006
3	Limbal Stem Cell Deficiency 05/2021 - 09/2005
3	Corneal Injuries 05/2015 - 10/2006
3	Optic Nerve Diseases (Optic Neuropathy) 06/2011 - 11/2008
2	Rhinosinusitis 01/2022 - 01/2021
2	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 03/2014
2	Hyperglycemia 01/2022 - 07/2020
2	Eye Diseases (Eye Disease) 10/2021 - 01/2015
2	Myopia 12/2020 - 01/2012
2	Melanoma (Melanoma, Malignant) 09/2020 - 01/2020
2	Ganglion Cysts (Ganglion) 05/2020 - 04/2019
2	Wounds and Injuries (Trauma) 04/2020 - 09/2014
2	Vision Disorders (Hemeralopia) 01/2018 - 01/2015
2	Retinal Degeneration 01/2017 - 01/2017
2	Pain (Aches) 01/2017 - 10/2015
2	Foreign Bodies (Foreign Body) 01/2017 - 05/2003
2	Keratoconus 06/2015 - 11/2005
2	Substance-Related Disorders (Drug Abuse) 05/2015 - 09/2014
2	Benign Mucous Membrane Pemphigoid (Cicatricial Pemphigoid) 01/2015 - 08/2011
2	Herpetic Keratitis 01/2014 - 01/2008
2	Rosacea (Acne Rosacea) 10/2013 - 09/2009
2	Corneal Ulcer 07/2010 - 07/2007
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2010 - 12/2004
2	Ocular Hypertension (Glaucoma, Suspect) 12/2008 - 10/2005
1	Atopic Dermatitis (Atopic Eczema) 03/2022
1	Conjunctivitis 03/2022
1	Obesity 01/2022
1	Nasal Polyps (Nasal Polyp) 01/2022
1	Metabolic Diseases (Metabolic Disease) 01/2022
1	Choroidal Neovascularization 10/2021
1	Breast Neoplasms (Breast Cancer) 05/2021

Drug/Important Bio-Agent (IBA)

41	Nerve Growth Factor (NGF)IBA 01/2022 - 10/2003
14	Ophthalmic Solutions (Eye Drops)IBA 01/2020 - 03/2003
12	Retinaldehyde (Retinal)IBA 01/2022 - 11/2008
7	Nerve Growth Factors (Neurotrophins)IBA 12/2019 - 10/2008
6	CytokinesIBA 07/2020 - 01/2003
5	AntibodiesIBA 10/2020 - 10/2003
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 03/2014
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2006
4	NeuropeptidesIBA 10/2019 - 10/2008
4	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2019 - 10/2011
4	SteroidsIBA 12/2018 - 07/2010
4	Toll-Like Receptors (Toll-Like Receptor)IBA 05/2011 - 09/2005
3	Pharmaceutical PreparationsIBA 03/2022 - 10/2009
3	Neuroprotective AgentsIBA 04/2019 - 08/2009
2	Complement System Proteins (Complement)IBA 01/2022 - 04/2019
2	Biological ProductsIBA 10/2021 - 06/2005
2	Therapeutic UsesIBA 12/2020 - 08/2009
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 04/2019 - 12/2013
2	Endothelial Growth FactorsIBA 11/2018 - 01/2016
2	Fluorescein (Funduscein)FDA LinkGeneric 01/2017 - 08/2011
2	Gonadal Steroid Hormones (Sex Hormones)IBA 05/2016 - 01/2015
2	Doxycycline (Periostat)FDA LinkGeneric 10/2013 - 09/2009
2	Substance PIBA 01/2011 - 10/2008
2	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 01/2011 - 10/2008
2	Neuropeptide YIBA 01/2011 - 10/2008
2	Peptides (Polypeptides)IBA 01/2011 - 12/2006
2	Matrix Metalloproteinases (MMPs)IBA 09/2009 - 08/2009
2	Metalloproteases (Metalloproteinases)IBA 09/2009 - 10/2003
2	Messenger RNA (mRNA)IBA 12/2006 - 10/2003
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2006 - 10/2003
1	Lipopolysaccharide ReceptorsIBA 07/2022
1	pimecrolimus (Elidel)FDA Link 03/2022
1	dupilumabIBA 03/2022
1	Monoclonal AntibodiesIBA 01/2022
1	benralizumabIBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022
1	SirtuinsIBA 01/2022
1	Interferon-gamma (Interferon, gamma)IBA 01/2022
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2022
1	AntimetabolitesIBA 10/2021
1	Bevacizumab (Avastin)FDA Link 10/2021
1	Lapatinib (GW572016)FDA Link 05/2021
1	Capecitabine (Xeloda)FDA Link 05/2021

Therapy/Procedure

14	Therapeutics 01/2022 - 07/2010
3	Slit Lamp 05/2021 - 01/2008
3	Aftercare (After-Treatment) 12/2020 - 03/2003
3	Vitrectomy 05/2020 - 04/2008
2	Drug Therapy (Chemotherapy) 05/2021 - 08/2009
2	Intravitreal Injections 04/2019 - 11/2018
2	Duration of Therapy 10/2013 - 11/2009